Comprehensive Pharmacokinetic Evaluation of High Melanin Binder Levofloxacin in Rabbits Shows Potential of Topical Eye Drops for Posterior Segment Treatment.

چکیده

The purpose of this work was to understand the impact of melanin binding on ocular pharmacokinetics after administration of a high-binder model drug via different administration routes. We applied levofloxacin to pigmented and albino rabbits as eye drops (single and multiple), as well as by…

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موضوعات مرتبط

• درمان های ضد VEGF