Differential Effect of Aldosterone or Mineralocorticoid Receptor Overexpression on Retinal Inflammation.

چکیده

Overactivation of the mineralocorticoid receptor (MR) pathway is proinflammatory and contributes to the pathogenesis of diabetic retinopathy and of age-related macular degeneration. Excess of aldosterone, the specific MR ligand, is known to stimulate the production of proinflammatory cytokines and…

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