Efficacy and safety of methotrexate in the treatment of proliferative vitreoretinopathy: a systematic review.

چکیده

Proliferative Vitreoretinopathy (PVR) is a major complication of surgical repair for Rhegmatogenous Retinal Detachment (RRD). Methotrexate (MTX), a folate antimetabolite, has shown promise in targeting the pathological processes involved in PVR, such as cell proliferation inhibition, fibrosis and…

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