Genetic Loss of RORα Impairs Visual Function With Rod Bipolar Cell Degeneration In Mice.

چکیده

Retinoic acid receptor-related orphan receptor alpha (RORα) is a ligand-dependent nuclear receptor involved in eye development and diseases. Genetic variations of RORα have been linked with the development of age-related macular degeneration, yet whether RORα regulates visual function is unknown.…

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