Investigative ophthalmology & visual science۲۰۲۵نمایه شده در PubMed
Emma M Hartness, Hanna Shevalye, Jessica M Skeie, Timothy Eggleston, Matthew G Field, Gregory A Schmidt, Pornpoj Phruttiwanichakun, Aliasger K Salem, Mark A Greiner
چکیده
Evidence suggests that corneal endothelial cell (CEC) death in Fuchs endothelial corneal dystrophy (FECD) is due to ferroptosis, an iron-mediated cell death. Iron-sulfur cluster (ISC)-containing aconitases and the iron responsive element binding proteins IREBP1 and IREBP2 are known mediators of…
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DOI: 10.1167/iovs.66.4.23