Mettl3-Mediated m6A Modification is Essential for Visual Function and Retinal Photoreceptor Survival.

چکیده

N6-methyladenosine (m6A) modification, one of the most common epigenetic modifications in eukaryotic mRNA, has been shown to play a role in the development and function of the mammalian nervous system by regulating the biological fate of mRNA. METTL3, the catalytically active component of the m6A…

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