Single-Cell Sequencing Analysis Reveals Dysregulated Energy Metabolism and Altered Synaptic Connectivity in the Mouse Retina Following Dark Rearing.

چکیده

In this study, single-cell RNA sequencing (scRNA-seq) was applied to retinas from dark-reared and normally reared mice to resolve how each cell type contributes to retinal alterations under visual deprivation. C57BL/6J mice were reared in complete darkness from birth to postnatal day 36 (P36), when…

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