The PERK-p38 MAPK Axis Drives Endoplasmic Reticulum Stress-Induced Apoptosis in Fuchs Endothelial Corneal Dystrophy.

چکیده

To investigate the role of p38 mitogen-activated protein kinase (MAPK) in endoplasmic reticulum (ER) stress-induced corneal endothelial cell death in Fuchs endothelial corneal dystrophy (FECD) and to evaluate its potential as a therapeutic target. Three complementary ER stress models were utilized:…

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