Investigative ophthalmology & visual science۲۰۲۵۲ استنادنمایه شده در PubMed
Araceli Lara-López, Klaudia Gonzalez-Imaz, María Rodríguez-Hidalgo, Miren Sarasola-Gastesi, Leire Escudero-Arrarás, Santiago Milla-Navarro, Pedro de la Villa, Maialen Sagartzazu-Aizpurua, José Ignacio Miranda, Jesús María Aizpurua, Adolfo López de Munain, Ainara Vallejo-Illarramendi, Javier Ruiz-Ederra
چکیده
This study evaluates the therapeutic potential of MP-004, a novel FKBP12 ligand, in the treatment of inherited retinal dystrophies (IRDs). MP-004 targets the FKBP12/RyR interaction, which is disrupted in several neurologic disorders with underlying oxidative stress. The toxicity and efficacy of…
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DOI: 10.1167/iovs.66.3.56